Njengamanje, amabhizinisi amaningi asebenzisa ipuleti nohlaka, i-centrifugation nezinye izindlela zokususa amabhaktheriya kanye nokungcola okuthile kwama-macromolecular kumhluzi wokuvutshelwa.Uketshezi lokuphakelayo oluhlukaniswe ngale ndlela lunokuqukethwe okuphezulu kokungcola okuncibilikayo, umthamo woketshezi oluphakelayo olukhulu, kanye nokucaca koketshezi oluphakelayo oluphansi, okuholela ekusebenzeni okuphansi kwezindlela zokuhlanza njengeresin noma ukukhishwa kwinqubo elandelayo, okubuye kwenyuse izindleko zokukhiqiza."I-Bona Bio" isebenzise ngempumelelo ubuchwepheshe bokuhlukaniswa kwe-membrane ekukhiqizeni ukukhishwa kokungcola kanye nokuhlanzwa komhluzi wokuvutshelwa, ixazulule ngempumelelo izinkinga zokuhlukaniswa, ukuhlanzwa kanye nokugxila ekukhiqizeni okuthuthukisiwe komhluzi wokuvutshelwa, futhi ngasikhathi sinye kufezwe inhloso yamandla. ukonga, ukunciphisa ukusetshenziswa kanye nokukhiqiza okuhlanzekile.Inikeza izixazululo ezongayo, eziphambili nezinengqondo zamabhizinisi okuvutshelwa.
Izinzuzo zobuchwepheshe bokuhlukaniswa kwe-membrane:
1. Ukunemba okuphezulu kokuhlunga kwe-membrane kuqinisekisa umphumela wokucaciswa koketshezi lwe-biological fermentation, olunezinzuzo ezinkulu uma kuqhathaniswa nenqubo evamile, ukususwa kokungcola kuphelele, futhi ikhwalithi yomkhiqizo iyathuthukiswa ngokusobala.
2. Ukuhlunga kwe-membrane kwenziwa endaweni evaliwe, ngezinga eliphezulu lokuzenzekelayo, futhi inqubo yokuhlunga inciphisa ukuchithwa komhluzi wokuvutshelwa kanye nokungcola emikhiqizweni.
3. Inqubo yokuhlunga i-membrane ingasebenza ekushiseni okuvamile (25 ° C), akukho ukuguqulwa kwesigaba, ukuguqulwa kwekhwalithi, akukho ukusabela kwamakhemikhali, akukho monakalo ezithanjeni ezisebenzayo, akukho monakalo ezingxenyeni ezizwela ukushisa, futhi kunciphisa kakhulu ukusetshenziswa kwamandla.
4. Inqubo yokuhlunga i-Membrane, i-mycelium ingatholwa ngenkathi icacisa, isusa ukungcola, igxilisa futhi ihlanza umkhiqizo;
5. Imishini yokuhlushwa ye-membrane ine-flux enkulu, isivinini sokugxila okusheshayo, nenqubo ezinzile nethembekile;
6. Ukugxiliswa kwe-Membrane kunokunemba okuphezulu kokuhlunga, futhi uketshezi oluhlungiwe lunokuhlanzeka okuphezulu.Ingacatshangelwa ukuthi iphinde isetshenziswe ekukhiqizeni, okunciphisa ukuchithwa kwendle futhi inokubaluleka okuhle kokuvikela imvelo;
7. Izinga le-automation liphezulu, liphephile futhi linokwethenjelwa, linciphisa ngempumelelo amandla okusebenza, futhi inqubo yokuhlunga ulwelwesi lwenziwa esitsheni esivaliwe ukuze kuzuzwe ukukhiqizwa okuhlanzekile;
8. Isici se-membrane sinendawo enkulu yokugcwalisa kanye nendawo encane yesistimu, ekulungele ukuguqulwa kwezobuchwepheshe, ukunwetshwa noma amaphrojekthi amasha amafektri amadala, anganciphisa ngokuphumelelayo izindleko zokukhiqiza kanye nokutshalwa kwezimali.
Manje, umhleli weShandong Bona Group uzokwethula ukusetshenziswa kobuchwepheshe bokuhlukanisa ulwelwesi kumhluzi we-biological fermentation.
1. Ukufaka isicelo ngemuva kokwelashwa kwama-antibiotics
Kunemikhiqizo ephumayo, amaprotheni aphakathi nendawo ancibilikayo ku-penicillin fermentation filtrate, okuzodala i-emulsification ngesikhathi sokukhipha.Kunzima ukuhlukanisa isigaba se-aqueous kanye nesigaba se-ester, esithinta ukudluliswa kwe-penicillin phakathi kwezigaba ezimbili, ukwandisa isikhathi senqubo yokukhipha, futhi kunciphisa ukugxila kwe-penicillin esigabeni sokukhipha kanye nesivuno.Ukwelashwa komhluzi we-penicillin fermentation nge-membrane ye-ultrafiltration kungasusa ngempumelelo amaprotheni nokunye ukungcola kwe-macromolecular futhi kuqede i-emulsification ngesikhathi sokukhishwa.Ngemuva kwe-ultrafiltration, wonke amaprotheni ancibilikayo ayagcinwa, futhi isivuno esiphelele se-ultrafiltration kanye nokukhishwa kwe-penicillin ngokuyisisekelo kufana nesivuno sokuqala sokukhishwa, futhi ukuhlukaniswa kwesigaba kulula ukukufeza ngesikhathi sokukhishwa, okunciphisa ukulahlekelwa kwe-solvent, akudingi ukwengeza i-demulsifier. , futhi kunciphisa izindleko.
2. Isicelo ngemuva kokucubungula amavithamini
I-Vitamin C iwumkhiqizo ojwayelekile wamavithamini okhiqizwa ukuvutshelwa.Ucwaningo oluningi lwenziwe ekwelapheni umhluzi we-Vc fermentation ngobuchwepheshe be-membrane, futhi ukuthuthukiswa kwezimboni sekufezeke ngempumelelo kakade.I-Vc ivutshelwa yi-sorbitol ngaphansi kwesenzo samagciwane ukwenza i-gulonic acid ephakathi, ebuye iguqulwe futhi ikhiqizwe ngemva kokuhlanzwa.I-Gulonic acid fermentation broth yenziwa kuqala ukuze isuse ukungcola okuqinile namanye amaprotheni, bese i-ultrafiltration ukuze isuse ukungcola kwama-macromolecular njengamaprotheni nama-polysaccharides, ukuhlanza uketshezi lokuphakelayo kungena esinyathelweni esilandelayo sokushintshana kwe-ion, kukhuphule izinga lokushintshana kwekholomu yokushintshanisa ion nokunciphisa. uketshezi lokuvuselela kanye nokusetshenziswa kwamanzi okugeza, ngaleyo ndlela kunciphisa inqubo yokushintshisana ngesinyathelo esisodwa kanye nokonga amandla.Uma belashwa nge-reverse osmosis membrane, amanzi amaningi oketshezi olusetshenziswayo angasuswa, esikhundleni sokugxiliswa kwezinga lokuqala kanye nenqubo yokuhwamuka ekukhiqizeni.Ukwamukelwa kobuchwepheshe be-membrane kunciphisa inqubo yokukhipha i-proto-gulonic acid, kunciphisa inani le-acid-base regeneration uketshezi lwemfucuza kanye namanzi okuhlanza, futhi kunciphisa ukulahlekelwa kokubola okushisayo kwe-gulonic acid phakathi nenqubo yokuhlushwa, ukunciphisa izindleko zokukhiqiza.
3. Ukufakwa kwe-amino acid ngemuva kokucubungula
Amanzi angcolile e-Monosodium glutamate angawamanzi angcolile ane-high-concentration refractory organic, angagcini nje ngokuba nokuqukethwe okuphezulu kwezinto eziphilayo, kodwa futhi aqukethe i-NH4+ ephezulu kanye ne-SO4^2-.Kunzima ngobuchwepheshe bokwelapha bebhayoloji bendabuko ukuyenza ihlangabezane nokukhishwa okujwayelekile.Ulwelwesi lwe-Ultrafiltration lusetshenziselwa ukususa amagciwane namagciwane emanzini angcolile e-monosodium glutamate.Amaprotheni ama-macromolecular nezinye izakhi, izinga lokukhishwa kwe-SS emanzini angcolile lingafinyelela ngaphezu kwama-99%, futhi izinga lokususwa kwe-CODcr licishe libe ngu-30%, elinganciphisa ukucutshungulwa kwendlela yebhayoloji futhi libuyisele amaprotheni emanzini angcolile.
Ubuchwepheshe bokuhlukanisa ama-Membrane bunobuhle bemishini elula, ukusebenza okulula, ukusebenza kahle okuphezulu kokucubungula nokonga amandla, futhi busetshenziswe kabanzi emikhakheni ehlukahlukene.Ngokuthuthuka kwesayensi nobuchwepheshe, ubuchwepheshe bokuhlukanisa ulwelwesi buzothuthukiswa ngokuqhubekayo futhi busetshenziswe ezimbonini eziningi.
Isikhathi sokuthumela: Apr-20-2022